Publication: Lanostane derivatives from the leaves and twigs of Garcinia wallichii
Issued Date
2020-08-01
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ISSN
18767486
18743900
18743900
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2-s2.0-85086605969
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Mahidol University
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SCOPUS
Bibliographic Citation
Phytochemistry Letters. Vol.38, (2020), 101-106
Suggested Citation
Sasitorn Jaitheerapapkul, Chutima Kuhakarn, Sakchai Hongthong, Natthinee Anantachoke, Sariyarach Thanasansurapong, Arthit Chairoungdua, Kanoknetr Suksen, Narong Nuntasaen, Vichai Reutrakul Lanostane derivatives from the leaves and twigs of Garcinia wallichii. Phytochemistry Letters. Vol.38, (2020), 101-106. doi:10.1016/j.phytol.2020.05.005 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/57591
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Title
Lanostane derivatives from the leaves and twigs of Garcinia wallichii
Abstract
© 2020 Phytochemical Society of Europe Bioassay-guided purification of the n-hexane and ethyl acetate extracts of the leaves and twigs of Garcinia wallichii led to the isolation of four previously undescribed lanostane triterpenes, wallichinanes F–I (1–4), together with four known compounds, wallichinane A (5), wallichinane B (6), friedelin (7), and lupeol (8). All structures were determined by means of spectroscopic techniques as well as comparison with literature data. Some isolated compounds were evaluated for cytotoxicity against a panel of cultured mammalian cancer cell lines. Wallichinanes G and H displayed weak cytotoxicity, whereas wallichinanes A, B, and F were found to be inactive in all the tested cell lines.