Publication: Improving quality of colonoscopy by adding simethicone to sodium phosphate bowel preparation
Issued Date
2009-06-28
Resource Type
ISSN
10079327
Other identifier(s)
2-s2.0-67651240430
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
World Journal of Gastroenterology. Vol.15, No.24 (2009), 3032-3037
Suggested Citation
Sasinee Tongprasert, Abhasnee Sobhonslidsuk, Sasivimol Rattanasiri Improving quality of colonoscopy by adding simethicone to sodium phosphate bowel preparation. World Journal of Gastroenterology. Vol.15, No.24 (2009), 3032-3037. doi:10.3748/wjg.15.3032 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/28043
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Improving quality of colonoscopy by adding simethicone to sodium phosphate bowel preparation
Other Contributor(s)
Abstract
Aim: To evaluate the effectiveness of simethicone in enhancing visibility and efficacy during colonoscopy. Methods: A prospective, double-blind, randomized, placebo-controlled study was conducted. One hundred and twenty-four patients were allocated to receive 2 doses of sodium phosphate plus 240 mg of tablet simethicone or placebo as bowel preparation. Visibility was blindly assessed for the amount of air bubbles and adequacy of colon preparation. Total colonoscopic time, side effects of the medication, endoscopist and patient satisfaction were also compared. Results: Sodium phosphate plus simethicone, compared to sodium phosphate plus placebo, improved visibility by diminishing air bubbles (100.00% vs 42.37%, P < 0.0001) but simethicone failed to demonstrate improvement in adequacy of colon preparation (90.16% vs 81.36%, P = 0.17). Endoscopist and patient satisfaction were increased significantly in the simethicone group. However, there was no difference in the total duration of colonoscopy and side effects of the medication. Conclusion: The addition of simethicone is of benefit for colonoscopic bowel preparation by diminishing air bubbles, which results in enhanced visibility. Endoscopist and patient satisfaction is also increased. © 2009 The WJG Press and Baishideng. All rights reserved.