Publication:
Hb G-Makassar [β6(A3)Glu→Ala; codon 6 (GAG→GCG)]: Molecular characterization, clinical, and hematological effects

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dc.contributor.authorVip Viprakasiten_US
dc.contributor.authorAranya Wiriyasateinkulen_US
dc.contributor.authorBenjamas Sattayasevanaen_US
dc.contributor.authorKatie L. Milesen_US
dc.contributor.authorVichai Laosombaten_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherPrince of Songkla Universityen_US
dc.contributor.otherJohn Radcliffe Hospitalen_US
dc.date.accessioned2018-07-24T02:56:13Z
dc.date.available2018-07-24T02:56:13Z
dc.date.issued2002-10-30en_US
dc.description.abstractWe report a Thai family in which five members are Hb G-Makassar heterozygotes and one member is, in addition, a heterozygote for β0-thalassemia (IVS-I-1, G → T). We confirm that the previously presumed mutation at codon 6 of the β-globin gene is GAG → GCG. Hb G-Makassar heterozygotes are asymptomatic and hematologically normal. The Hb G-Makassar/β0-thalassemia compound heterozygote has features of thalassemia minor. A simple and rapid polymerase chain reaction-restriction fragment length polymorphism for the detection of Hb G-Makassar is described.en_US
dc.identifier.citationHemoglobin. Vol.26, No.3 (2002), 245-253en_US
dc.identifier.doi10.1081/HEM-120015028en_US
dc.identifier.issn03630269en_US
dc.identifier.other2-s2.0-0036401279en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/20034
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0036401279&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectMedicineen_US
dc.titleHb G-Makassar [β6(A3)Glu→Ala; codon 6 (GAG→GCG)]: Molecular characterization, clinical, and hematological effectsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0036401279&origin=inwarden_US

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