Publication:
Localized periorbital edema induced by ibuprofen

Issued Date

2005-01-01

Resource Type

Article

ISSN

13468138
03852407

DOI

10.1111/j.1346-8138.2005.tb00883.x

Other identifier(s)

2-s2.0-32944472946

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Dermatology. Vol.32, No.12 (2005), 969-971

Suggested Citation

Piti Palungwachira, Pranee Palungwachira, Hideoki Ogawa Localized periorbital edema induced by ibuprofen. Journal of Dermatology. Vol.32, No.12 (2005), 969-971. doi:10.1111/j.1346-8138.2005.tb00883.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/17112

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Title

Localized periorbital edema induced by ibuprofen

Author(s)

Piti Palungwachira
 Pranee Palungwachira
 Hideoki Ogawa

Other Contributor(s)

Srinakharinwirot University
 Mahidol University
 Juntendo University

Abstract

We documented localized periorbital edema in one patient with ibuprofen sensitivity without underlying chronic urticaria. The reaction developed one hour after ingestion of 200 mg of ibuprofen. No systemic symptoms were observed. No other NSAIDs did not induce symptoms. This patient was able to tolerate doses of ibuprofen after pretreatment with terfenadine. These observations suggest that histamine played a central role in this ibuprofen-induced skin reaction. Treatment with terfenadine enabled the patient to tolerate ibuprofen without experiencing any side effects. To the best of our knowledge, this is the first reported case of periorbital edema induced by ibuprofen.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/17112

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Scopus 2001-2005