Publication: Antioxidant and hepatoprotective activities of Thai mango seed kernel extract
7
Issued Date
2009-01-01
Resource Type
ISSN
14390221
00320943
00320943
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2-s2.0-70349525500
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Mahidol University
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SCOPUS
Bibliographic Citation
Planta Medica. Vol.75, No.10 (2009), 1118-1123
Suggested Citation
Saruth Nithitanakool, Pimolpan Pithayanukul, Rapepol Bavovada Antioxidant and hepatoprotective activities of Thai mango seed kernel extract. Planta Medica. Vol.75, No.10 (2009), 1118-1123. doi:10.1055/s-0029-1185507 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/27320
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Title
Antioxidant and hepatoprotective activities of Thai mango seed kernel extract
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Abstract
Three polyphenolic principles, 1,2,3,4,6-penta-Ogalloyl-β-D- glucopyranose (PGG), methyl gallate (MG), and gallic acid (GA), were isolated from the ethanolic extract of seed kernels of Thai mango (MSKE) (Mangifera indica L.cv. "Fahlun") and quantified using a TLC scanning densitometric method. The MSKE and its isolates were investigated by studying their antioxidant capacities using four different methods, by determining their in vitro anti-inflammatory activities, and by evaluating their hepatoprotective potential against liver injury in rats induced by carbon tetrachloride (CCl4). The hepatoprotective effect of MSKE is clearly supported by its polyphenolic nature of the main principle, PGG, which exhibited potent antioxidant and anti-inflammatory activities.