Publication: Factors associated with acute renal failure in severe falciparum Malaria patients
Issued Date
2010-09-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-79952114412
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.41, No.5 (2010), 1042-1047
Suggested Citation
Suparp Vannaphan, Nick Walters, Thotsaporn Saengnedsawang, Noppadon Tangpukdee, Patcharin Kham-In, Molleudee Klubprasit, Polrat Wilairatana, Sornchai Looareesuwan Factors associated with acute renal failure in severe falciparum Malaria patients. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.41, No.5 (2010), 1042-1047. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/29546
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Factors associated with acute renal failure in severe falciparum Malaria patients
Other Contributor(s)
Abstract
Acute renal failure (ARF) is a common cause of morbidity and mortality in severe malaria infection. We evaluated factors associated with acute renal failure in severe malaria by comparing patients with severe malaria with and without ARF admitted to the Hospital for Tropical Diseases, Bangkok, Thailand. Nine hundred fifteen severe malaria patients were included in the study, of whom 195 had ARF and 720 did not have ARF. We found jaundice, anemia, hypoalbuminemia, hyponatremia, hyperkalemia, acidosis, leukocytosis, elevated transaminases (SGOT and SGPT) and cerebral malaria, were significantly associated with ARF among patients with severe malaria (p<0.05). Patients who have ARF and any of these clinical or laboratory manifestations of severe malaria should be monitored and managed properly, since early detection and treatment may reduce morbidity and mortality.