Publication:
Site-Specific Synthesis of β-Fluorinated γ-Butyrolactams via Decarboxylative Fluorination of β-Carboxyl-γ-Butyrolactams

Issued Date

2019-01-01

Resource Type

Article

ISSN

10990690
1434193X

DOI

10.1002/ejoc.201900685

Other identifier(s)

2-s2.0-85069882375

Rights

Mahidol University

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SCOPUS

Bibliographic Citation

European Journal of Organic Chemistry. Vol.2019, No.29 (2019), 4710-4720

Suggested Citation

Supasorn Phae-nok, Manat Pohmakotr, Chutima Kuhakarn, Vichai Reutrakul, Darunee Soorukram Site-Specific Synthesis of β-Fluorinated γ-Butyrolactams via Decarboxylative Fluorination of β-Carboxyl-γ-Butyrolactams. European Journal of Organic Chemistry. Vol.2019, No.29 (2019), 4710-4720. doi:10.1002/ejoc.201900685 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/50582

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Title

Site-Specific Synthesis of β-Fluorinated γ-Butyrolactams via Decarboxylative Fluorination of β-Carboxyl-γ-Butyrolactams

Author(s)

Supasorn Phae-nok
 Manat Pohmakotr
 Chutima Kuhakarn
 Vichai Reutrakul
 Darunee Soorukram

Other Contributor(s)

Mahidol University

Abstract

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Monofluorinated cyclic nitrogen-containing compounds are synthetically useful scaffolds in organic synthesis and medicinal applications. In this report, AgNO3 mediated decarboxylative fluorination of β-carboxyl-γ-butyrolactams using Selectfluor® as a fluorine source was described to achieve a site-specific synthesis of β-fluorinated γ-butyrolactams.

Keyword(s)

Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/50582

Collections

Scopus 2019