Publication: Alterations in membrane proteins of mouse erythrocytes infected with different species and strains of malaria parasites
Issued Date
1979-01-01
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ISSN
03050491
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2-s2.0-0018760869
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Mahidol University
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SCOPUS
Bibliographic Citation
Comparative Biochemistry and Physiology -- Part B: Biochemistry and. Vol.63, No.1 (1979), 83-85
Suggested Citation
Yongyuth Yuthavong, Prapon Wilairat, Bhinyo Panijpan, Chariyada Potiwan, G. H. Beale Alterations in membrane proteins of mouse erythrocytes infected with different species and strains of malaria parasites. Comparative Biochemistry and Physiology -- Part B: Biochemistry and. Vol.63, No.1 (1979), 83-85. doi:10.1016/0305-0491(79)90238-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/13162
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Title
Alterations in membrane proteins of mouse erythrocytes infected with different species and strains of malaria parasites
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Abstract
1. 1. The membrane fraction, prepared by hypotonic lysis, of mouse red cells infected with Plasmodium berghei, P. yoelii YM, P. yoelii 17 X, P. yoelii 33 X, P. vinckei or P. chabaudi shows significant alterations from normal in protein composition as observed by dodecylsulphate-polyacrylamide gel electrophoresis. 2. 2. There is a reduction in intensity of various protein bands, notably bands I and II (spectrin), of membranes prepared from infected red cells. 3. 3. New bands are observed as a result of infection, the intensity and location of which depend on the parasite species and strain. A new band of apparent molecular weight 150,000 appears with a strong intensity in P. yoelii YM infection, with a moderate intensity in P. berghei infection, and with a weak intensity in P. vinckei and P. chabaudi infection. In P. yoelii 17X and 33X infection, multiple weak bands are seen in the molecular weight range 120,000-210,000. © 1979.
