Publication: Patients with uninjured lungs may also benefit from lung-protective ventilator settings
Issued Date
2017-01-01
Resource Type
ISSN
1759796X
20461402
20461402
Other identifier(s)
2-s2.0-85034948312
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Mahidol University
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SCOPUS
Bibliographic Citation
F1000Research. Vol.6, (2017)
Suggested Citation
Ary Serpa Neto, Roger Alencar, Vittorio D'Angelo, Rachel Carmona, Marcus J. Schultz Patients with uninjured lungs may also benefit from lung-protective ventilator settings. F1000Research. Vol.6, (2017). doi:10.12688/f1000research.12225.1 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/42091
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Title
Patients with uninjured lungs may also benefit from lung-protective ventilator settings
Abstract
© 2017 Alencar R et al. Although mechanical ventilation is a life-saving strategy in critically ill patients and an indispensable tool in patients under general anesthesia for surgery, it also acts as a double-edged sword. Indeed, ventilation is increasingly recognized as a potentially dangerous intrusion that has the potential to harm lungs, in a condition known as 'ventilator-induced lung injury' (VILI). So-called 'lung-protective' ventilator settings aiming at prevention of VILI have been shown to improve outcomes in patients with acute respiratory distress syndrome (ARDS), and, over the last few years, there has been increasing interest in possible benefit of lung-protective ventilation in patients under ventilation for reasons other than ARDS. Patients without ARDS could benefit from tidal volume reduction during mechanical ventilation. However, it is uncertain whether higher levels of positive end-expiratory pressure could benefit these patients as well. Finally, recent evidence suggests that patients without ARDS should receive low driving pressures during ventilation.