Publication:
Loss to followup in HIV-infected patients from Asia-pacific region: Results from TAHOD

Issued Date

2012-12-01

Resource Type

Article

ISSN

20901259
20901240

DOI

10.1155/2012/375217

Other identifier(s)

2-s2.0-84873877453

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

AIDS Research and Treatment. Vol.2012, (2012)

Suggested Citation

Jialun Zhou, Junko Tanuma, Romanee Chaiwarith, Christopher K.C. Lee, Matthew G. Law, Nagalingeswaran Kumarasamy, Praphan Phanuphak, Yi Ming A. Chen, Sasisopin Kiertiburanakul, Fujie Zhang, Saphonn Vonthanak, Rossana Ditangco, Sanjay Pujari, Jun Yong Choi, Tuti Parwati Merati, Evy Yunihastuti, Patrick C.K. Li, Adeeba Kamarulzaman, Van Kinh Nguyen, Thi Thanh Thuy Pham, Poh Lian Lim Loss to followup in HIV-infected patients from Asia-pacific region: Results from TAHOD. AIDS Research and Treatment. Vol.2012, (2012). doi:10.1155/2012/375217 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/14491

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Title

Loss to followup in HIV-infected patients from Asia-pacific region: Results from TAHOD

Author(s)

Jialun Zhou
 Junko Tanuma
 Romanee Chaiwarith
 Christopher K.C. Lee
 Matthew G. Law
 Nagalingeswaran Kumarasamy
 Praphan Phanuphak
 Yi Ming A. Chen
 Sasisopin Kiertiburanakul
 Fujie Zhang
 Saphonn Vonthanak
 Rossana Ditangco
 Sanjay Pujari
 Jun Yong Choi
 Tuti Parwati Merati
 Evy Yunihastuti
 Patrick C.K. Li
 Adeeba Kamarulzaman
 Van Kinh Nguyen
 Thi Thanh Thuy Pham
 Poh Lian Lim

Other Contributor(s)

University of New South Wales (UNSW) Australia
 National Center for Global Health and Medicine
 Research Institute for Health Sciences
 Hospital Sungai Buloh
 YR Gaitonde Centre for AIDS Research and Education
 The HIV Netherlands Australia Thailand Research Collaboration
 National Yang-Ming University Taiwan
 Mahidol University
 Capital Medical University China
 National Center for HIV/AIDS
 Gokila
 Institute of Infectious Diseases
 Yonsei University College of Medicine
 Universitas Udayana
 University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
 Queen Elizabeth Hospital Hong Kong
 University of Malaya Medical Centre
 National Hospital for Tropical Diseases
 Bach Mai Hospital
 Tan Tock Seng Hospital

Abstract

This study examined characteristics of HIV-infected patients in the TREAT Asia HIV Observational Database who were lost to follow-up (LTFU) from treatment and care. Time from last clinic visit to 31 March 2009 was analysed to determine the interval that best classified LTFU. Patients defined as LTFU were then categorised into permanently LTFU (never returned) and temporary LTFU (re-entered later), and these groups compared. A total of 3626 patients were included (71% male). No clinic visits for 180 days was the best-performing LTFU definition (sensitivity 90.6%, specificity 92.3%). During 7697 person-years of follow-up, 1648 episodes of LFTU were recorded (21.4 per 100-person-years). Patients LFTU were younger (P = 0.002), had HIV viral load ≥500 copies/mL or missing (P = 0.021), had shorter history of HIV infection (P = 0.048), and received no, single- or double-antiretroviral therapy, or a triple-drug regimen containing a protease inhibitor (P < 0.001). 48% of patients LTFU never returned. These patients were more likely to have low or missing haemoglobin (P < 0.001), missing recent HIV viral load (P < 0.001), negative hepatitis C test (P = 0.025), and previous temporary LTFU episodes (P < 0.001). Our analyses suggest that patients not seen at a clinic for 180 days are at high risk of permanent LTFU, and should be aggressively traced. © 2012 Jialun Zhou et al.

Keyword(s)

Medicine

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URI

https://repository.li.mahidol.ac.th/handle/123456789/14491

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