Publication:
Mortality rates in HIV-infected patients with second failure of antiretroviral therapy are still high: A lesson from NA-ACCORD

Issued Date

2010-04-01

Resource Type

Note

ISSN

17448336
14787210

DOI

10.1586/eri.10.18

Other identifier(s)

2-s2.0-77950793606

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Expert Review of Anti-Infective Therapy. Vol.8, No.4 (2010), 371-373

Suggested Citation

Somnuek Sungkanuparph Mortality rates in HIV-infected patients with second failure of antiretroviral therapy are still high: A lesson from NA-ACCORD. Expert Review of Anti-Infective Therapy. Vol.8, No.4 (2010), 371-373. doi:10.1586/eri.10.18 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/29245

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Title

Mortality rates in HIV-infected patients with second failure of antiretroviral therapy are still high: A lesson from NA-ACCORD

Author(s)

Somnuek Sungkanuparph

Other Contributor(s)

Mahidol University

Abstract

In clinical practice, a significant proportion of HIV-infected patients still experience treatment failure during antiretroviral therapy (ART). There is limited information regarding the second treatment failure and its mortality rate. This article assessed the findings of a recently published paper describing analyzed data from the North American AIDS Cohort Collaboration on Research and Design. A total of 7159 out of 36,188 patients who received ART had a second virologic failure from ART. Although the risk of second failure decreased from 1996 to 2005 owing to the evolution of ART, the cumulative mortality at 5 years after onset of second failure was 26%. Strategies to prevent treatment failure are urgently needed in order to minimize the mortality among HIV-infected patients receiving ART. © 2010 Expert Reviews Ltd.

Keyword(s)

Immunology and Microbiology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/29245

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Scopus 2006-2010