Publication:
Synthesis of aryl α-keto esters via the rearrangement of aryl cyanohydrin carbonate esters

3

Issued Date

2003-01-27

Resource Type

Article

ISSN

00404039

DOI

10.1016/S0040-4039(02)02725-9

Other identifier(s)

2-s2.0-0037467813

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Tetrahedron Letters. Vol.44, No.5 (2003), 1019-1021

Suggested Citation

Nopporn Thasana, Vilailak Prachyawarakorn, Sopchok Tontoolarug, Somsak Ruchirawat Synthesis of aryl α-keto esters via the rearrangement of aryl cyanohydrin carbonate esters. Tetrahedron Letters. Vol.44, No.5 (2003), 1019-1021. doi:10.1016/S0040-4039(02)02725-9 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/20770

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Title

Synthesis of aryl α-keto esters via the rearrangement of aryl cyanohydrin carbonate esters

Author(s)

Nopporn Thasana
 Vilailak Prachyawarakorn
 Sopchok Tontoolarug
 Somsak Ruchirawat

Other Contributor(s)

Chulabhorn Research Institute
 Mahidol University

Abstract

A facile synthesis of aryl α-keto esters is reported involving the rearrangement of aryl cyanohydrin carbonate esters induced by the α-carbanion to the nitrile group generated by LDA. However, under similar conditions, an o-benzyloxycyanohydrin carbonate ester rearranged via a domino reaction leading to 2-phenylbenzofuran-3-carboxylic acid. © 2003 Elsevier Science Ltd. All rights reserved.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/20770

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Scopus 2001-2005