Publication: Adaptive and cross-protective responses against cadmium and zinc toxicity in cadmium-resistant bacterium isolated from a zinc mine
Issued Date
2009-01-01
Resource Type
ISSN
16784405
15178382
15178382
Other identifier(s)
2-s2.0-70350155010
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Brazilian Journal of Microbiology. Vol.40, No.4 (2009), 838-845
Suggested Citation
Benjaphorn Prapagdee, Anchulee Watcharamusik Adaptive and cross-protective responses against cadmium and zinc toxicity in cadmium-resistant bacterium isolated from a zinc mine. Brazilian Journal of Microbiology. Vol.40, No.4 (2009), 838-845. doi:10.1590/S1517-83822009000400014 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/27744
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Title
Adaptive and cross-protective responses against cadmium and zinc toxicity in cadmium-resistant bacterium isolated from a zinc mine
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Abstract
Cadmium (Cd) is a major environmental hazard, which usually is detected in its ionic form of Cd2+. It also causes adverse toxic effects on human health and other living organisms. Cd-resistant bacteria were isolated from Cd-contaminated soils. One isolate, TAK1, was highly resistance level to Cd toxicity. TAK1 was isolated from soil contaminated with a high Cd concentration (204.1 mg.kg-1). The result of 16S rDNA sequence analysis found that the TAK1 showed the similarity to Ralstonia sp. Physiological adaptive and cross-protective responses to Cd and Zn killing were investigated in Ralstonia sp.TAK1. Exposure to a low concentration of Cd induced adaptive resistance to higher concentrations of Cd. In addition, pretreatment of Ralstonia sp.TAK1 with an inducing concentration of Cd conferred cross-protective response against subsequent exposure to the lethal concentrations of Zn. The induced adaptive and cross-protective response Ralstonia sp.TAK1 required newly synthesized protein(s). Cd-induced adaptive and cross-protective responses against Cd and Zn toxicity are the important mechanisms used by Ralstonia sp.TAK1 to survive in the heavy metal contaminated environments. These findings might lead to the use of Ralstonia sp.TAK1 for microbial based remediation in Cd and Zn-contaminated soils.