Publication: Branch pulmonary artery regurgitation in repaired tetralogy of fallot: Correlation with pulmonary artery morphology, distensibility, and right ventricular function
Issued Date
2021-09-01
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ISSN
2379139X
23791381
23791381
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2-s2.0-85114256749
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Mahidol University
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SCOPUS
Bibliographic Citation
Tomography. Vol.7, No.3 (2021), 412-423
Suggested Citation
Suvipaporn Siripornpitak, Duangkanok Lueangwattanapong, Apichaya Sriprachyakul, Suthep Wanitkun, Alisa Limsuwan Branch pulmonary artery regurgitation in repaired tetralogy of fallot: Correlation with pulmonary artery morphology, distensibility, and right ventricular function. Tomography. Vol.7, No.3 (2021), 412-423. doi:10.3390/tomography7030036 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/77896
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Title
Branch pulmonary artery regurgitation in repaired tetralogy of fallot: Correlation with pulmonary artery morphology, distensibility, and right ventricular function
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Abstract
Background: The aim was to determine the effect of pulmonary artery (PA) morphology on the branch pulmonary artery-regurgitation fraction (BPA-RF), the relationship of pulmonary insuffi-ciency (PI) to BPA-RF and PA-distensibility, and factors (BPA-RF and PA-distensibility) associated with right ventricular function (RVF) in repaired tetralogy of Fallot (rTOF). Methods: A total of 182 rTOF patients (median age 17.1 years) were analyzed for length, angle of PA, BPA-RF, PI, and PA-distensibility, using magnetic resonance imaging. Results: The left PA had a significant greater RF than the right PA (median (interquartile range)): LPA 43.1% (32.6–51.5) and RPA 35.2% (24.7–44.7), p < 0.001. The LPA was shorter with a narrower angle than the RPA (p < 0.001). The anatomy of the branch-PA was not a factor for the greater LPA-RF (odds ratio, 95% confidence interval: CI, p-value): length 0.44 (0.95–2.00), p = 0.28; angle 0.63 (0.13–2.99), p = 0.56. There was a strong positive correlation between PI and BPA-RF-coefficients (95% CI), p-value: LPA 0.78% (0.70–0.86), p < 0.001; RPA 0.78% (0.71–0.84), p < 0.001 and between BPA-RF and distensibility-coefficients (95%CI), p-value: LPA 0.73% (0.37–1.09), p < 0.001; RPA 1.63% (1.22–2.03), p < 0.001, respectively. The adjusted BPA-RF did not predict RVF, RPA (p = 0.434), LPA (p = 0.268). Conclusions: PA morphology is not a significant factor for the differential BPA-RF. The vascular wall in rTOF patients responds to chronic increased intravascular volume by increasing distensibility. BPA-RF is not a determinant of RVF.