Publication: Topical antiinflammatory activity of two pimarane diterpenes from Kaempferia pulchra
2
Issued Date
1996-01-01
Resource Type
ISSN
0951418X
Other identifier(s)
2-s2.0-0029803473
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Phytotherapy Research. Vol.10, No.6 (1996), 534-535
Suggested Citation
Ubonwan Pongprayoon, Tuanta Sematong, Patoomratana Tuchinda, Per Claeson, Vichai Reutrakul, Nilufar Nahar Topical antiinflammatory activity of two pimarane diterpenes from Kaempferia pulchra. Phytotherapy Research. Vol.10, No.6 (1996), 534-535. doi:10.1002/(SICI)1099-1573(199609)10:6<534::AID-PTR890>3.0.CO;2-C Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/17588
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Topical antiinflammatory activity of two pimarane diterpenes from Kaempferia pulchra
Other Contributor(s)
Abstract
Two diterpenes, 2α-acetoxysandraracopimaradien-1α-ol (1) and sandaracopimaradien-1α,2α-diol (2) isolated from Kaempferia pulchra Ridl. (Zingiberaceae), have been assayed for topical antiinflammatory activity in the model of 12-O-tetradecanoylphorbol-13-acetate-induced ear oedema in rats. Both substances were found active and the ID50-values were estimated to be 330 and 50 μg/ear, respectively. The ID50-value of the reference drug diclofenac was calculated to 90 μg/ear.