Publication: Assessment of temperature-dependent proteomes of Pythium insidiosum by using the SWISS-PROT database
| dc.contributor.author | Theerapong Krajaejun | en_US |
| dc.contributor.author | Onrapak Reamtong | en_US |
| dc.contributor.author | Tassanee Lohnoo | en_US |
| dc.contributor.author | Wanta Yingyong | en_US |
| dc.contributor.author | Ratchainant Thammasudjarit | en_US |
| dc.contributor.other | Faculty of Medicine, Ramathibodi Hospital, Mahidol University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2020-01-27T09:27:30Z | |
| dc.date.available | 2020-01-27T09:27:30Z | |
| dc.date.issued | 2019-10-01 | en_US |
| dc.description.abstract | © The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. Pythium insidiosum causes the life-threatening disease, called pythiosis. Information on microbial pathogenesis could lead to an effective method of infection control. This study aims at assessing temperature-dependent proteomes, and identifying putative virulence factors of P. insidiosum. Protein extracts from growths at 25°C and 37°C were analyzed by mass spectrometry and SWISS-PROT database. A total of 1052 proteins were identified. Upon exposure to increased temperature, 219 proteins were markedly expressed, eight of which were putative virulence factors of P. insidiosum. These temperature-dependent proteins should be further investigated for their roles in pathogenesis, and some of which could be potential therapeutic targets. | en_US |
| dc.identifier.citation | Medical mycology. Vol.57, No.7 (2019), 918-921 | en_US |
| dc.identifier.doi | 10.1093/mmy/myy164 | en_US |
| dc.identifier.issn | 14602709 | en_US |
| dc.identifier.other | 2-s2.0-85072148493 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/51377 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85072148493&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Assessment of temperature-dependent proteomes of Pythium insidiosum by using the SWISS-PROT database | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85072148493&origin=inward | en_US |