Publication:
Genetic Variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries

Issued Date

2014-04-03

Resource Type

Article

ISSN

19326203

DOI

10.1371/journal.pone.0093942

Other identifier(s)

2-s2.0-84899412014

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

PLoS ONE. Vol.9, No.4 (2014)

Suggested Citation

Naowarat Tanomsing, Mayfong Mayxay, Paul N. Newton, Francois Nosten, Christiane Dolecek, Tran Tinh Hien, Nicholas J. White, Nicholas P.J. Day, Arjen M. Dondorp, Mallika Imwong Genetic Variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. PLoS ONE. Vol.9, No.4 (2014). doi:10.1371/journal.pone.0093942 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/33028

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Title

Genetic Variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries

Author(s)

Naowarat Tanomsing
 Mayfong Mayxay
 Paul N. Newton
 Francois Nosten
 Christiane Dolecek
 Tran Tinh Hien
 Nicholas J. White
 Nicholas P.J. Day
 Arjen M. Dondorp
 Mallika Imwong

Other Contributor(s)

Mahidol University
 Mahosot Hospital
 University of Health Sciences
 Nuffield Department of Clinical Medicine
 UCL

Abstract

The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance. © 2014 Tanomsing et al.

Keyword(s)

Agricultural and Biological Sciences
 Biochemistry, Genetics and Molecular Biology

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/33028

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