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The toxicity of betel nut extract determined by inhibition of microbial dehydrogenase activity

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dc.contributor.authorSittichai Koontongkaewen_US
dc.contributor.authorBoonyanit Thaweboonen_US
dc.contributor.authorRungsunn Tungtrongchitren_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-02-27T04:30:09Z
dc.date.available2018-02-27T04:30:09Z
dc.date.issued1986-01-01en_US
dc.description.abstractDimethyl sulfoxide extracts of betel nut (100g/L) and betel leaf (100g/L), and methanol and water extracts of betel nut (100g/L) were found to inhibit dehydrogenase activity of Bacillus subtilis. In contrast betel nut (100g/L) extracted by petroleum ether showed no inhibitory effect. Thin layer chromatography, ultraviolet spectroscopy and total polyphenols estimation indicated that betel nut contained large amounts of polyphenols. On the basis of toxicity assessment, the results implied that betel nuts and betel leaves contained a hydrophilic element which was toxic to living cells. Copyright © 1986 Wiley Periodicals, Inc., A Wiley Companyen_US
dc.identifier.citationToxicity Assessment. Vol.1, No.4 (1986), 419-429en_US
dc.identifier.doi10.1002/tox.2540010404en_US
dc.identifier.issn10982256en_US
dc.identifier.issn08848181en_US
dc.identifier.other2-s2.0-0022904935en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/9873
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0022904935&origin=inwarden_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleThe toxicity of betel nut extract determined by inhibition of microbial dehydrogenase activityen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0022904935&origin=inwarden_US

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