Publication: Novel subcutaneous low-molecular-weight heparin injection technique to reduce post-injection bruising
Issued Date
2019-07-01
Resource Type
ISSN
14333031
02683555
02683555
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2-s2.0-85059354385
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Mahidol University
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SCOPUS
Bibliographic Citation
Phlebology. Vol.34, No.6 (2019), 399-405
Suggested Citation
Sommapun Jueakaew, Rattana Piancharoensin, Natchayakorn Pinkesorn, Sarunya Thippayarom, Nuttawut Sermsathanasawadi Novel subcutaneous low-molecular-weight heparin injection technique to reduce post-injection bruising. Phlebology. Vol.34, No.6 (2019), 399-405. doi:10.1177/0268355518813512 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/51553
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Title
Novel subcutaneous low-molecular-weight heparin injection technique to reduce post-injection bruising
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Abstract
© The Author(s) 2018. Objective: To investigate the efficacy of a novel low-molecular-weight heparin injection technique compared to the standard technique relative to bruising incidence, bruise size, and pain. Methods: A randomized controlled trial was conducted in 44 patients with acute deep vein thrombosis. Patients who were randomized into the control group received a 10-s duration injection with immediate needle withdrawal, whereas study group patients received a 30-s duration injection with a 10-s pause before needle withdrawal. Two injection sites were assessed for pain and bruising between 48 and 60 h after injection. Results: Bruises occurred in 50.0% and 18.2% of control and study group patients, respectively (p = 0.03). Mean bruise size between 48 and 60 h after injection was 172.73 ± 372.60 mm2 and 28.18 ± 70.01 mm2 in the control group and study group, respectively (p = 0.026). Pain scores were comparable between groups. Conclusion: A 30-s duration injection with a 10-s pause before needle withdrawal resulted in significantly fewer and smaller bruises.