Publication: Estimation of plasma insulin from plasma glucose
Issued Date
2002-11-01
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ISSN
00189294
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2-s2.0-0036846872
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Mahidol University
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SCOPUS
Bibliographic Citation
IEEE Transactions on Biomedical Engineering. Vol.49, No.11 (2002), 1253-1259
Suggested Citation
Chatchai Neatpisarnvanit, John Robert Boston Estimation of plasma insulin from plasma glucose. IEEE Transactions on Biomedical Engineering. Vol.49, No.11 (2002), 1253-1259. doi:10.1109/TBME.2002.804599 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/20161
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Title
Estimation of plasma insulin from plasma glucose
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Abstract
Two plasma insulin estimators are derived and evaluated in this paper. The estimators use continuously monitored plasma glucose, and they are based on a simple mathematical model of glucose-insulin metabolism. The first estimator (Estimator 1) was obtained from the glucose subsystem of the simplified model, which includes plasma glucose and interstitial insulin compartments. The second estimator (Estimator 2) was developed from the insulin kinetics subsystem of the simplified model. The performances of the estimators were compared using computer simulations and data from clinical intravenous glucose tolerance test procedures and from animal experiments.