Publication: 9-vinylanthracene based fluorogens: Synthesis, structure-property relationships and applications
Issued Date
2017-12-01
Resource Type
ISSN
14203049
Other identifier(s)
2-s2.0-85040162303
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Molecules. Vol.22, No.12 (2017)
Suggested Citation
Mengjie Liu, Sawaros Onchaiya, Lewis Yi Fong Tan, Mohammad A. Haghighatbin, Tracey Luu, Tze Cin Owyong, Roozbeh Hushiarian, Conor F. Hogan, Trevor A. Smith, Yuning Hong 9-vinylanthracene based fluorogens: Synthesis, structure-property relationships and applications. Molecules. Vol.22, No.12 (2017). doi:10.3390/molecules22122148 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/41730
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
9-vinylanthracene based fluorogens: Synthesis, structure-property relationships and applications
Other Contributor(s)
Abstract
© 2017 by the authors. Fluorescent dyes with aggregation-induced emission (AIE) properties exhibit intensified emission upon aggregation. They are promising candidates to study biomolecules and cellular changes in aqueous environments when aggregation formation occurs. Here, we report a group of 9-position functionalized anthracene derivatives that were conveniently synthesized by the palladium-catalyzed Heck reaction. Using fluorometric analyses, these dyes were confirmed to show AIE behavior upon forming aggregates at high concentrations, in viscous solvents, and when poorly solubilized. Their photophysical properties were then further correlated with their structural features, using density functional theory (DFT) calculation. Finally, we demonstrated their potential applications in monitoring pH changes, quantifying globular proteins, as well as cell imaging with confocal microscopy.
