Publication: Erectile dysfunction and atrial fibrillation: A systematic review and meta-analysis
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Issued Date
2018-08-01
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ISSN
14422042
09198172
09198172
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2-s2.0-85050509758
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal of Urology. Vol.25, No.8 (2018), 752-757
Suggested Citation
Ronpichai Chokesuwattanaskul, Charat Thongprayoon, Pavida Pachariyanon, Konika Sharma, Patompong Ungprasert, Tarun Bathini, Wisit Cheungpasitporn Erectile dysfunction and atrial fibrillation: A systematic review and meta-analysis. International Journal of Urology. Vol.25, No.8 (2018), 752-757. doi:10.1111/iju.13725 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/46490
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Title
Erectile dysfunction and atrial fibrillation: A systematic review and meta-analysis
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Abstract
© 2018 The Japanese Urological Association Objective: To investigate the pooled incidence or the prevalence of erectile dysfunction, and to assess the risk of erectile dysfunction in patients with atrial fibrillation. Methods: A systematic review was carried out in the MEDLINE, EMBASE and Cochrane databases from inception through January 2018 to identify: (i) studies that reported the incidence and/or prevalence of erectile dysfunction in atrial fibrillation patients; or (ii) studies that assessed the association between atrial fibrillation and erectile dysfunction. Pooled odds ratios and 95% confidence intervals were calculated using a random effects model. Results: Five observational studies (27 841 patients) were enrolled. The pooled estimated prevalence of erectile dysfunction in atrial fibrillation patients was 57% (95% confidence interval 50–64, I2 = 0). A study showed an incidence of newly diagnosed erectile dysfunction in atrial fibrillation patients of 0.96% during the mean follow-up duration of 4.67 ± 3.20 years. There was a significant association of atrial fibrillation with an increased risk of erectile dysfunction, with a pooled odds ratio of 1.79 (95% confidence interval 1.44–2.23, I2 = 0%). The data on the risk of atrial fibrillation development in patients with erectile dysfunction were limited. A study showed the comparable risk of atrial fibrillation in patients with erectile dysfunction (odds ratio 1.03, 95% confidence interval 0.67–1.5), when compared with those without erectile dysfunction. Conclusions: The present study suggests a significant association between erectile dysfunction and atrial fibrillation. The overall estimated prevalence of erectile dysfunction among atrial fibrillation patients is 57%. However, despite limited data, the current evidence suggests a low incidence of new erectile dysfunction in atrial fibrillation patients.