Publication: YAP-depleted iPSC MUSIi012-A-2 maintained all normal stem cell characteristics
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Issued Date
2020-03-01
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ISSN
18767753
18735061
18735061
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2-s2.0-85078655191
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Mahidol University
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SCOPUS
Bibliographic Citation
Stem Cell Research. Vol.43, (2020)
Suggested Citation
Chanchao Lorthongpanich, Chuti Laowtammathron, Nittaya Jiamvoraphong, Pimonwan Srisook, Pimjai Chingsuwanrote, Phatchanat Klaihmon, Nattaya Damkham, Papussorn Terbto, Supaporn Waeteekul, Yaowalak U-pratya, Surapol Issaragrisil YAP-depleted iPSC MUSIi012-A-2 maintained all normal stem cell characteristics. Stem Cell Research. Vol.43, (2020). doi:10.1016/j.scr.2020.101723 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/53574
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Title
YAP-depleted iPSC MUSIi012-A-2 maintained all normal stem cell characteristics
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Abstract
© 2020 The Author(s) Yes-associated protein (YAP) is an important transcriptional coactivator in the Hippo signaling pathway. Using CRISPR/Cas9 technology, we established a stable YAP-knockdown (YAP-KD) induced pluripotent stem cell (iPSC) from the MUSIi012-A cell line. The YAP-KD iPSC MUSIi012-A-2 maintained the pluripotent phenotype, the ability to differentiate into all three embryonic germ layers, and it maintained the normal karyotype.