Publication: Antimycobacterial pimarane diterpenes from the fungus Diaporthe sp.
Issued Date
2003-04-07
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ISSN
0960894X
Other identifier(s)
2-s2.0-0037424702
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Mahidol University
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SCOPUS
Bibliographic Citation
Bioorganic and Medicinal Chemistry Letters. Vol.13, No.7 (2003), 1253-1255
Suggested Citation
Suppamit Dettrakul, Prasat Kittakoop, Masahiko Isaka, Sombat Nopichai, Chotika Suyarnsestakorn, Morakot Tanticharoen, Yodhathai Thebtaranonth Antimycobacterial pimarane diterpenes from the fungus Diaporthe sp.. Bioorganic and Medicinal Chemistry Letters. Vol.13, No.7 (2003), 1253-1255. doi:10.1016/S0960-894X(03)00111-2 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/20744
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Title
Antimycobacterial pimarane diterpenes from the fungus Diaporthe sp.
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Abstract
Two new pimarane diterpenes, diaportheins A (1) and B (2), were isolated from a culture broth of the fungus Diaporthe sp. BCC 6140. Diaporthein B (2) strongly inhibited the growth of Mycobacterium tuberculosis with the MIC value of 3.1 μg/mL, while diaporthein A (1) showed only mild activity (MIC value of 200 μg/mL). © 2003 Elsevier Science Ltd. All rights reserved.