Publication: In vitro screening of 10 edible thai plants for potential antifungal properties
Issued Date
2014-02-04
Resource Type
ISSN
17414288
1741427X
1741427X
Other identifier(s)
2-s2.0-84893157913
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Evidence-based Complementary and Alternative Medicine. Vol.2014, (2014)
Suggested Citation
Supattra Suwanmanee, Thitinan Kitisin, Natthanej Luplertlop In vitro screening of 10 edible thai plants for potential antifungal properties. Evidence-based Complementary and Alternative Medicine. Vol.2014, (2014). doi:10.1155/2014/138587 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/34298
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
In vitro screening of 10 edible thai plants for potential antifungal properties
Other Contributor(s)
Abstract
Growing rates of fungal infections and increasing resistance against standard antifungal drugs can cause serious health problems. There is, therefore, increasing interest in the potential use of medicinal plants as novel antifungal agents. This study investigates the antifungal properties of crude plant extracts from ten medicinal plant species. Crude samples were extracted using the hot water extraction process. The minimum inhibitory concentrations (MIC) and diameter zone of inhibition were determined in each extract against ten fungal strains, and fluconazole was used as a positive control. The cytotoxicity of crude extracts on in vitro human skin fibroblast (HSF) cell models was determined by MTT assay. Of the ten crude extracts, Psidium guajava L. exhibited the highest antifungal activity, diameter zone of inhibition, and percentage HSF cell viability. Although all extracts exhibited antifungal activity, Psidium guajava L. had the greatest potential for developing antifungal treatments. © 2014 Supattra Suwanmanee et al.