Publication: Spread of antimicrobial-resistant salmonella from poultry to humans in thailand
Issued Date
2021-01-01
Resource Type
ISSN
18842836
13446304
13446304
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2-s2.0-85107088468
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Mahidol University
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SCOPUS
Bibliographic Citation
Japanese Journal of Infectious Diseases. Vol.74, No.3 (2021), 220-227
Suggested Citation
Paweena Kongsanan, Sunpetch Angkititrakul, Anong Kiddee, Chanwit Tribuddharat Spread of antimicrobial-resistant salmonella from poultry to humans in thailand. Japanese Journal of Infectious Diseases. Vol.74, No.3 (2021), 220-227. doi:10.7883/yoken.JJID.2020.548 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/78716
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Title
Spread of antimicrobial-resistant salmonella from poultry to humans in thailand
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Abstract
SUMMARY: Food animal production is important for every country. Several antibiotic agents are used in poultry farming to reduce the economic losses arising from mostly untested infectious diseases. This continued study was performed to determine the prevalence of antibiotic-resistant Salmonella in broiler chickens, poultry farmers, and Salmonella bacteremia patients. A total of 121 Salmonella isolates were collected from the Thai provinces of Khon Kaen (65 isolates), Ratchaburi (43 isolates), and Phayao (13 isolates). Salmonella from chicken showed a high rate of resistance to nalidixic acid and tetracycline. Sixty-four percent of Salmonella isolates carried class 1 integrons (intI1 gene-positive). Among the 121 Salmonella isolates, there were 15 serotypes, with S. Enteritidis being the most common. A clonal relationship between the chicken and human isolates was demonstrated by 3 molecular typing methods: enterobacterial repetitive intergenic consensus polymerase chain reaction; pulsed-field gel electrophoresis; and high-throughput multilocus sequence typing. A spread of the sequence type 11 clone was found between chickens and humans. This study revealed a large-scale Salmonella outbreak in Thailand, a link between resistant bacteria from poultry farms and vertical transmission through the food chain, and horizontal transmission of resistance genes. These results can be used for future surveillance and monitoring.