Publication: Susceptibility of community-acquired pathogens to antibiotics in Africa and Asia in neonates - an alarmingly short review
Issued Date
2011-02-01
Resource Type
ISSN
13653156
13602276
13602276
Other identifier(s)
2-s2.0-78651459698
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Mahidol University
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SCOPUS
Bibliographic Citation
Tropical Medicine and International Health. Vol.16, No.2 (2011), 145-151
Suggested Citation
Yoel Lubell, Elizabeth A. Ashley, Claudia Turner, Paul Turner, Nicholas J. White Susceptibility of community-acquired pathogens to antibiotics in Africa and Asia in neonates - an alarmingly short review. Tropical Medicine and International Health. Vol.16, No.2 (2011), 145-151. doi:10.1111/j.1365-3156.2010.02686.x Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/12088
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Title
Susceptibility of community-acquired pathogens to antibiotics in Africa and Asia in neonates - an alarmingly short review
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Abstract
Objective To assess the susceptibility of community-acquired pathogens in neonatal sepsis to commonly prescribed antibiotics in sub-Saharan Africa and Asia since 2002.Methods Literature review in PubMed and Embase. Susceptibility was estimated for pathogens individually and stratified by region. Isolates were also classified into Gram positive and Gram negative pathogens to estimate their pooled susceptibility. Results and conclusions Only nine studies met the inclusion criteria. The available data indicated poor susceptibility to almost all commonly used antibiotics in pathogens such as Staphylococcus aureus and Klebsiella spp. Only Streptococcus pneumoniae exhibited good susceptibility to all drugs other than cotrimoxazole. The extreme scarcity of data prevents drawing any firm conclusions beyond the urgent need for more studies to identify the best treatments for neonatal sepsis in the developing world. © 2010 Blackwell Publishing Ltd.