Publication: Generation of induced pluripotent stem cells derived from a 77-year-old healthy woman as control for age related diseases
Issued Date
2016-11-01
Resource Type
ISSN
18767753
18735061
18735061
Other identifier(s)
2-s2.0-85028045546
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Mahidol University
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SCOPUS
Bibliographic Citation
Stem Cell Research. Vol.17, No.3 (2016), 550-552
Suggested Citation
Natakarn Nimsanor, Ida Jørring, Mikkel A. Rasmussen, Christian Clausen, Ulrike A. Mau-Holzmann, Christine Bus, Susanna A. Hoffmann, Thomas Gasser, Torsten Kluba, Bjørn Holst, Benjamin Schmid Generation of induced pluripotent stem cells derived from a 77-year-old healthy woman as control for age related diseases. Stem Cell Research. Vol.17, No.3 (2016), 550-552. doi:10.1016/j.scr.2016.09.019 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/42887
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Title
Generation of induced pluripotent stem cells derived from a 77-year-old healthy woman as control for age related diseases
Abstract
© 2016 Michael Boutros, German Cancer Research Center, Heidelberg, Germany Induced pluripotent stem cells (iPSCs) hold great promise to model diseases, where the disease affected cell type is difficult to access. A major obstacle for the development of disease models is the lack of well characterized control iPSCs from old people not affected by such a disease. Furthermore, gene-editing approaches often require iPSCs from healthy donors, where pathogenic mutations can be inserted if patient material is not available. Here, we report the generation of an iPSC line (16423 #6) from a 77-year-old woman, who did not display any disease symptoms at the time, when the skin biopsy was taken.
