Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.4 (2006), 619-621
Suggested Citation
Saranya Auparakkitanon, Prapon Wilairat Antimalarial activity of concanamycin A alone and in combination with pyronaridine. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.4 (2006), 619-621. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/23701
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Antimalarial activity of concanamycin A alone and in combination with pyronaridine
Concanamycin A, a macrolide antibiotic inhibitor of vacuolar H +-ATPase derived from Streptomyces sp, inhibited Plasmodium falciparum K1 growth in culture with an IC50 value of 0.2 nM. It exhibited an additive effect when tested together with the antimalarial pyronaridine.
