Publication:
Comparison of the efficacy and safety of 0.1% tacrolimus ointment and 0.1% mometasone furoate cream for adult vitiligo: A single-blinded pilot study

Issued Date

2016-12-01

Resource Type

Article

ISSN

2223330X
10278117

DOI

10.1016/j.dsi.2016.05.005

Other identifier(s)

2-s2.0-84994804659

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Dermatologica Sinica. Vol.34, No.4 (2016), 177-179

Suggested Citation

Narumol Silpa-Archa, Sunatra Nitayavardhana, Kanchalit Thanomkitti, Leena Chularojanamontri, Supenya Varothai, Chanisada Wongpraparut Comparison of the efficacy and safety of 0.1% tacrolimus ointment and 0.1% mometasone furoate cream for adult vitiligo: A single-blinded pilot study. Dermatologica Sinica. Vol.34, No.4 (2016), 177-179. doi:10.1016/j.dsi.2016.05.005 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/40971

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Title

Comparison of the efficacy and safety of 0.1% tacrolimus ointment and 0.1% mometasone furoate cream for adult vitiligo: A single-blinded pilot study

Author(s)

Narumol Silpa-Archa
 Sunatra Nitayavardhana
 Kanchalit Thanomkitti
 Leena Chularojanamontri
 Supenya Varothai
 Chanisada Wongpraparut

Other Contributor(s)

Mahidol University

Abstract

© 2016 Topical tacrolimus has demonstrated efficacy in vitiligo. This study compared the efficacy and safety of 0.1% tacrolimus ointment with 0.1% mometasone furoate cream in adult vitiligo. We enrolled patients with symmetrical, nonacral vitiligo, and the patients on each side were randomized to receive either 0.1% tacrolimus ointment or 0.1% mometasone furoate cream, applied twice daily for 6 months. Repigmentation outcome at 6 months was compared with baseline. Of 18 cases, 22% and 33% in tacrolimus and mometasone groups, respectively, displayed more than 50% repigmentation (p > 0.05). Telangiectasia was presented in one-third of cases on the mometasone-treated side. Both treatments were effective in vitiligo; however, 0.1% tacrolimus ointment has fewer adverse effects.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/40971

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Scopus 2016-2017