Publication:
Hexabromoacetone and ethyl tribromoacetate: a highly efficient reagent for bromination of alcohol

5

Issued Date

2008-02-11

Resource Type

Article

ISSN

00404039

DOI

10.1016/j.tetlet.2007.12.061

Other identifier(s)

2-s2.0-38349022154

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Tetrahedron Letters. Vol.49, No.7 (2008), 1146-1148

Suggested Citation

Pratoomrat Tongkate, Wanchai Pluempanupat, Warinthorn Chavasiri Hexabromoacetone and ethyl tribromoacetate: a highly efficient reagent for bromination of alcohol. Tetrahedron Letters. Vol.49, No.7 (2008), 1146-1148. doi:10.1016/j.tetlet.2007.12.061 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/18970

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Hexabromoacetone and ethyl tribromoacetate: a highly efficient reagent for bromination of alcohol

Author(s)

Pratoomrat Tongkate
 Wanchai Pluempanupat
 Warinthorn Chavasiri

Other Contributor(s)

Mahidol University

Abstract

A new and efficient method for the bromination of alcohols utilizing Br3CCOCBr3/PPh3and Br3CCO2Et/PPh3is described. Various alcohols can be converted smoothly into their corresponding alkyl bromides in high yields under mild conditions with short reaction times. Based upon1H NMR studies using competitive reactions between selected brominating agents and Cl3CCN, Br3CCOCBr3displays the highest reactivity approximately nine times that of CBr4. © 2007 Elsevier Ltd. All rights reserved.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/18970

Collections

Scopus 2006-2010