Publication:
Decreased parasite load and improved cognitive outcomes caused by deworming and consumption of multi-micronutrient fortified biscuits in rural Vietnamese schoolchildren

dc.contributor.authorTran T. Ngaen_US
dc.contributor.authorPattanee Winichagoonen_US
dc.contributor.authorMarjoleine A. Dijkhuizenen_US
dc.contributor.authorNguyen C. Khanen_US
dc.contributor.authorEmorn Wasantwisuten_US
dc.contributor.authorFrank T. Wieringaen_US
dc.contributor.otherNational Institute of Nutrition Vietnamen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherKobenhavns Universiteten_US
dc.contributor.otherIRD Centre de Montpellieren_US
dc.date.accessioned2018-05-03T08:15:42Z
dc.date.available2018-05-03T08:15:42Z
dc.date.issued2011-08-01en_US
dc.description.abstractMicronutrient deficiencies are associated with impaired growth and cognitive function. A school-based fortification program might benefit schoolchildren but a high prevalence of parasite infestation might affect effectiveness. A randomized, double-blind, placebo-controlled 2 x 2 factorial trial was conducted to assess the efficacy of multi-micronutrient fortified biscuits with or without de-worming on growth, cognitive function, and parasite load in Vietnamese schoolchildren. Schoolchildren (n = 510), 6-8 years of age were randomly allocated to receive albendazole or placebo at baseline and four months of multi-micronutrient fortified biscuits (FB) or non-fortified biscuits. Children receiving FB for four months scored higher on two cognitive tests: Raven's Colored Progressive Matrices and the Digit Span Forward test. Children receiving albendazole plus FB had the lowest parasite load after four months. In children receiving FB, mid-upper arm circumference was slightly improved (+0.082 cm) but there were no differences in other indexes of anthropometry. Combining multi-micronutrient fortified biscuits with de-worming is an effective strategy. Copyright © 2011 by The American Society of Tropical Medicine and Hygiene.en_US
dc.identifier.citationAmerican Journal of Tropical Medicine and Hygiene. Vol.85, No.2 (2011), 333-340en_US
dc.identifier.doi10.4269/ajtmh.2011.10-0651en_US
dc.identifier.issn00029637en_US
dc.identifier.other2-s2.0-80051510926en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/12017
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80051510926&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleDecreased parasite load and improved cognitive outcomes caused by deworming and consumption of multi-micronutrient fortified biscuits in rural Vietnamese schoolchildrenen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80051510926&origin=inwarden_US

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