Publication: Decreased parasite load and improved cognitive outcomes caused by deworming and consumption of multi-micronutrient fortified biscuits in rural Vietnamese schoolchildren
dc.contributor.author | Tran T. Nga | en_US |
dc.contributor.author | Pattanee Winichagoon | en_US |
dc.contributor.author | Marjoleine A. Dijkhuizen | en_US |
dc.contributor.author | Nguyen C. Khan | en_US |
dc.contributor.author | Emorn Wasantwisut | en_US |
dc.contributor.author | Frank T. Wieringa | en_US |
dc.contributor.other | National Institute of Nutrition Vietnam | en_US |
dc.contributor.other | Mahidol University | en_US |
dc.contributor.other | Kobenhavns Universitet | en_US |
dc.contributor.other | IRD Centre de Montpellier | en_US |
dc.date.accessioned | 2018-05-03T08:15:42Z | |
dc.date.available | 2018-05-03T08:15:42Z | |
dc.date.issued | 2011-08-01 | en_US |
dc.description.abstract | Micronutrient deficiencies are associated with impaired growth and cognitive function. A school-based fortification program might benefit schoolchildren but a high prevalence of parasite infestation might affect effectiveness. A randomized, double-blind, placebo-controlled 2 x 2 factorial trial was conducted to assess the efficacy of multi-micronutrient fortified biscuits with or without de-worming on growth, cognitive function, and parasite load in Vietnamese schoolchildren. Schoolchildren (n = 510), 6-8 years of age were randomly allocated to receive albendazole or placebo at baseline and four months of multi-micronutrient fortified biscuits (FB) or non-fortified biscuits. Children receiving FB for four months scored higher on two cognitive tests: Raven's Colored Progressive Matrices and the Digit Span Forward test. Children receiving albendazole plus FB had the lowest parasite load after four months. In children receiving FB, mid-upper arm circumference was slightly improved (+0.082 cm) but there were no differences in other indexes of anthropometry. Combining multi-micronutrient fortified biscuits with de-worming is an effective strategy. Copyright © 2011 by The American Society of Tropical Medicine and Hygiene. | en_US |
dc.identifier.citation | American Journal of Tropical Medicine and Hygiene. Vol.85, No.2 (2011), 333-340 | en_US |
dc.identifier.doi | 10.4269/ajtmh.2011.10-0651 | en_US |
dc.identifier.issn | 00029637 | en_US |
dc.identifier.other | 2-s2.0-80051510926 | en_US |
dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/123456789/12017 | |
dc.rights | Mahidol University | en_US |
dc.rights.holder | SCOPUS | en_US |
dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80051510926&origin=inward | en_US |
dc.subject | Immunology and Microbiology | en_US |
dc.subject | Medicine | en_US |
dc.title | Decreased parasite load and improved cognitive outcomes caused by deworming and consumption of multi-micronutrient fortified biscuits in rural Vietnamese schoolchildren | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | |
mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80051510926&origin=inward | en_US |