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A comparative study of the serological response to Japanese encephalitis vaccine in HIV-infected and uninfected Thai children

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dc.contributor.authorKulkanya Chokephaibulkiten_US
dc.contributor.authorNottasorn Plipaten_US
dc.contributor.authorSutee Yoksanen_US
dc.contributor.authorWanatpreeya Phongsamarten_US
dc.contributor.authorKeswadee Lappraen_US
dc.contributor.authorPimpanada Chearskulen_US
dc.contributor.authorSanay Chearskulen_US
dc.contributor.authorOrasri Wittawatmongkolen_US
dc.contributor.authorNirun Vanpraparen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-09-24T08:45:50Z
dc.date.available2018-09-24T08:45:50Z
dc.date.issued2010-04-30en_US
dc.description.abstractWe report a prospective study of mouse brain derived inactivated Japanese encephalitis (JE) vaccine, given in 3-dose EPI program to human immune deficiency virus (HIV)-exposed Thai infants. 18 HIV-infected receiving antiretroviral therapy with median baseline CD4 of 33.1%, and 92 HIV-uninfected children were studied. All but one HIV-infected child seroconverted after the second dose. The geometric mean titers (GMTs) 3 months after the second and third doses in HIV-infected vs HIV-uninfected children were 247 vs 938 (p = 0.022), and 2273 vs 24069 (p = 0.009), respectively. Urticaria or angioedema found in 4% and 6% in HIV-infected and -uninfected children, respectively (p = 1.0). The vaccine was safe and immunogenic but antibody response in HIV-infected children was not as high as in uninfected children. © 2010 Elsevier Ltd. All rights reserved.en_US
dc.identifier.citationVaccine. Vol.28, No.20 (2010), 3563-3566en_US
dc.identifier.doi10.1016/j.vaccine.2010.02.108en_US
dc.identifier.issn0264410Xen_US
dc.identifier.other2-s2.0-77950689387en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/28729
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950689387&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleA comparative study of the serological response to Japanese encephalitis vaccine in HIV-infected and uninfected Thai childrenen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950689387&origin=inwarden_US

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