Publication: Graves' disease complicating pregnancy
Issued Date
1993-12-01
Resource Type
ISSN
01252208
Other identifier(s)
2-s2.0-0027723990
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.76, No.7 (1993), 380-384
Suggested Citation
W. Phuapradit, R. Rajatanavin, N. Saropala, S. Hotrakit Graves' disease complicating pregnancy. Journal of the Medical Association of Thailand. Vol.76, No.7 (1993), 380-384. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/22626
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Title
Graves' disease complicating pregnancy
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Abstract
During the 12-yr period from 1981 to 1992, over 85,000 deliveries at Ramathibodi Hospital from 114 pregnancies (prevalence 0.1%) in 110 patients were complicated by Graves' disease. The diagnosis was made following conception in 52 per cent. Medical treatment with propylthiouracil was the main regimen. Maternal and perinatal outcome were related with thyroid status at delivery including thyrotoxic crisis, preeclampsia and preterm deliveries. There was no case of fetal goitre, hyperthyroidism, but fetal hypothyroidism occurred in 12.2 per cent which calls for close monitoring of antithyroid drug dosage and close neonatal-infant follow-up.