Publication: Cost-effectiveness of a tuberculosis active case finding program targeting household and neighborhood contacts in Cambodia
Issued Date
2014-01-01
Resource Type
ISSN
00029637
Other identifier(s)
2-s2.0-84900411552
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Mahidol University
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SCOPUS
Bibliographic Citation
American Journal of Tropical Medicine and Hygiene. Vol.90, No.5 (2014), 866-872
Suggested Citation
Rajendra P. Yadav, Nobuyuki Nishikiori, Peou Satha, Mao T. Eang, Yoel Lubell Cost-effectiveness of a tuberculosis active case finding program targeting household and neighborhood contacts in Cambodia. American Journal of Tropical Medicine and Hygiene. Vol.90, No.5 (2014), 866-872. doi:10.4269/ajtmh.13-0419 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34075
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Title
Cost-effectiveness of a tuberculosis active case finding program targeting household and neighborhood contacts in Cambodia
Abstract
In many high-risk populations, access to tuberculosis (TB) diagnosis and treatment is limited and pockets of high prevalence persist. We estimated the cost-effectiveness of an extensive active case finding program in areas of Cambodia where TB notifications and household poverty rates are highest and access to care is restricted. Thirty operational health districts with high TB incidence and household poverty were randomized into intervention and control groups. In intervention operational health districts, all household and symptomatic neighborhood contacts of registered TB patients of the past two years were encouraged to attend screening at mobile centers. In control districts, routine passive case finding activities continued. The program screened more than 35,000 household and neighborhood contacts and identified 810 bacteriologically confirmed cases. The cost-effectiveness analysis estimated that in these cases the reduction in mortality from 14% to 2% would result in a cost per daily adjusted life year averted of $330, suggesting that active case finding was highly cost-effective. Copyright © 2014 by The American Society of Tropical Medicine and Hygiene.