Publication: Salivary secretory IgA, pH, flow rates, mutans streptococci and Candida in children with rampant caries
Issued Date
2008-09-01
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ISSN
01251562
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2-s2.0-52649086751
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.39, No.5 (2008), 900-905
Suggested Citation
Sroisiri Thaweboon, Boonyanit Thaweboon, Siriruk Nakornchai, Sukritta Jitmaitree Salivary secretory IgA, pH, flow rates, mutans streptococci and Candida in children with rampant caries. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.39, No.5 (2008), 900-905. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/19540
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Title
Salivary secretory IgA, pH, flow rates, mutans streptococci and Candida in children with rampant caries
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Abstract
The aim of this study was to determine the levels of secretory IgA (SIgA), pH, flow rates, mutans streptococci (MS) and Candida in saliva of children with rampant caries compared to those caries-free. Thirty children (age 62-123 months) were enrolled and divided into two groups: Group I, children with rampant caries, Group II, caries-free children. The average salivary flow rate was measured from the volume yielded within 5 minutes and the pH was determined using a pH-electrode. Measurement of SIgA was performed using an immunoassay kit. The levels of MS and Candida were determined by culture on Mitis-Salivarius Bacitracin agar and Sabouraud dextrose agar. It was found that children with rampant caries presented with significantly higher levels of salivary SIgA, MS and Candida. However, the mean values for salivary flow rates and pH were similar between the groups. The results reveal that children with rampant caries had significantly higher levels of SIgA, MS and Candida in their oral cavities. This finding tends to support the hypothesis that higher levels of salivary SIgA may reflect a past exposure of the host to cariogenic microorganisms.