Publication: Ischemic stroke in young Asian women: Risk factors, subtypes and outcome
Issued Date
2010-09-01
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ISSN
10159770
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2-s2.0-77955625171
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Mahidol University
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SCOPUS
Bibliographic Citation
Cerebrovascular Diseases. Vol.30, No.4 (2010), 418-422
Suggested Citation
Mohammad Wasay, Subhash Kaul, Bindu Menon, Narayanaswamy Venketasubramanian, Padma Gunaratne, Ahmed Khalifa, Niphon Poungvarin, Mohammad Saadatnia, Robert Ngo Gan, Alper Dai, M. M. Mehndiratta Ischemic stroke in young Asian women: Risk factors, subtypes and outcome. Cerebrovascular Diseases. Vol.30, No.4 (2010), 418-422. doi:10.1159/000317075 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/29557
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Title
Ischemic stroke in young Asian women: Risk factors, subtypes and outcome
Other Contributor(s)
The Aga Khan University Hospital
Nizam's Institute of Medical Sciences
Sri Venkateswara Institute of Medical Sciences
G.B. Pant Hospital India
National Neuroscience Institute of Singapore
National Hospital of Sri Lanka
Damascus Hospital
Mahidol University
Isfahan University of Medical Sciences
Gaziantep Universitesi
Nizam's Institute of Medical Sciences
Sri Venkateswara Institute of Medical Sciences
G.B. Pant Hospital India
National Neuroscience Institute of Singapore
National Hospital of Sri Lanka
Damascus Hospital
Mahidol University
Isfahan University of Medical Sciences
Gaziantep Universitesi
Abstract
Background and Objective: The objective of our study was to describe risk factors, mechanisms and outcome of young Asian women with ischemic stroke. Methods: Twelve tertiary-care centers in 8 Asian countries participated. Women aged 15-45 years were included if they had an ischemic stroke supported by neuroimaging. Data on age, risk factor history, stroke mechanism and discharge status were collected. Results: A total of 958 subjects were included, their mean age was 34 years. Large-vessel thrombosis comprised 24%, cerebral venous thrombosis 21%, cardioembolism 19% and small-vessel thrombosis 15%. The stroke risk factors included hypertension (29%), diabetes (14%), pregnancy (11%), valvular heart disease (10%) and cigarette smoking (3%). Anemia was found in 42%, and mortality was 4%; at discharge, 17% had modified Rankin score (mRS) >4 and 83% mRS 0-3. Conclusion: Unlike among Caucasians, large-vessel thrombosis, cerebral venous thrombosis and cardioembolism are common among young Asian women with stroke. A high proportion are pregnancy-related. More studies are needed. Copyright © 2010 S. Karger AG.