Publication: Dyspepsia in acute falciparum malaria: a clinico-pathological correlation.
Issued Date
1992-12-01
Resource Type
ISSN
01251562
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2-s2.0-0027026458
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Mahidol University
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SCOPUS
Bibliographic Citation
The Southeast Asian journal of tropical medicine and public health. Vol.23, No.4 (1992), 788-794
Suggested Citation
P. Wilairatana, M. Riganti, S. Looareesuwan, B. Punpoowong, P. Srisopark, P. Charoenlarp Dyspepsia in acute falciparum malaria: a clinico-pathological correlation.. The Southeast Asian journal of tropical medicine and public health. Vol.23, No.4 (1992), 788-794. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/22345
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Title
Dyspepsia in acute falciparum malaria: a clinico-pathological correlation.
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Abstract
Gastrointestinal symptoms are common in acute falciparum malaria. Dyspepsia often occurs in such patients and sometimes it is exceptionally severe. However, the pathogenesis of the dyspeptic symptoms in malaria has not been clearly defined. Upper gastrointestinal endoscopy was performed in 40 patients with acute falciparum malaria in order to correlate the dyspeptic symptoms with the macroscopic (endoscopic) and microscopic (histologic) pathology of stomach and duodenum. The patients were divided into a dyspeptic group (n = 20, male/female ratio = 17/3, age range 18-50 years, mean age = 28.85 + 9.14 years), and a non-dyspeptic group (n = 20, male/female ratio = 16/4, age range 15-47, mean age 26.05 + 9.98 years). The findings revealed that dyspepsia correlated with topographic endoscopic pangastritis (p = 0.0014), the category of endoscopic antral gastritis (p = 0.013), and the histologic severity of antral gastritis (p = 0.0434). The results suggested that gastritis should be considered in acute falciparum malaria patients presenting with dyspepsia.