Publication: The Stability of Prostate-Specific Antigen in Semen Under Various Temperatures
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Issued Date
2015-11-01
Resource Type
ISSN
15564029
00221198
00221198
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2-s2.0-84955093547
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Forensic Sciences. Vol.60, No.6 (2015), 1577-1581
Suggested Citation
Supawon Srettabunjong, Parimol Betset, Suvit Limawongpranee, Pattama Ekpo The Stability of Prostate-Specific Antigen in Semen Under Various Temperatures. Journal of Forensic Sciences. Vol.60, No.6 (2015), 1577-1581. doi:10.1111/1556-4029.12791 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/35348
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Title
The Stability of Prostate-Specific Antigen in Semen Under Various Temperatures
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Abstract
© 2015 American Academy of Forensic Sciences. Prostate-specific antigen (PSA) is most commonly used for identifying semen, especially in the absence of sperm. However, PSA concentration varies according to storage temperature and duration, and little is known about its stability in semen. This study was therefore aimed to determine the stability under five different temperatures: -80, -20, 4, 25, and 37°C; and nine different durations: 1, 2, 3, 5, 7, 14, 30, 90, and 180 days. All samples were stored at -80°C after being secreted from the volunteers' body until analyzed. Results showed that the PSA concentration declined significantly over time under all temperatures studied except -80°C. At -20 and 4°C, PSA was still detectable on Day 180 with 50% and 70% decrease from its original concentration, respectively. At 25 and 37°C, PSA was detected up to Day 7 and 3, respectively. This information might assist forensic scientists understand more about PSA nature and integrate it into their works.