Southeast Asian Journal of Tropical Medicine and Public Health. Vol.16, No.2 (1985), 248-252
Suggested Citation
S. Pungpak, D. Bunnag, T. Harinasuta Studies on the chemotherapy of human opisthorchiasis: Effective dose of praziquantel in heavy infection. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.16, No.2 (1985), 248-252. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/30830
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Studies on the chemotherapy of human opisthorchiasis: Effective dose of praziquantel in heavy infection
Nine-six patients who had heavy Opisthorchis viverrini infection were studied. Egg count per gramme of faeces ranged from 10,800 to 139,000 (mean 26,044.3). Praziquantel 50 mg per kg body weight was given after a morning meal. 68 patients completed the follow up period of 60 days. The cure rate was 97.0%. The side-effects occurred on 61 patients (89.7%). The common side effects were diarhoea, dizziness, sleepiness, epigastric pain, headache, nausea and anorexia. These side-effects were mild and transient. 62 patients (91.2%) showed clinical improvement and 20 patients were symptom free on day 60.
