Publication: Hypochlorite solution for root canal irrigation that lacks a chlorinated odor
Issued Date
2017-01-01
Resource Type
ISSN
13057464
13057456
13057456
Other identifier(s)
2-s2.0-85020496071
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
European Journal of Dentistry. Vol.11, No.2 (2017), 221-225
Suggested Citation
La ongthong Vajrabhaya, Vanida Sangalungkarn, Ratchapin Srisatjaluk, Suwanna Korsuwannawong, Chareerut Phruksaniyom Hypochlorite solution for root canal irrigation that lacks a chlorinated odor. European Journal of Dentistry. Vol.11, No.2 (2017), 221-225. doi:10.4103/ejd.ejd_354_16 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/42468
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Hypochlorite solution for root canal irrigation that lacks a chlorinated odor
Other Contributor(s)
Abstract
© 2017 European Journal of Dentistry. Objectives: This is an in vitro study to develop a formulation of a hypochlorite solution for root canal irrigation that lacks a chlorinated odor. The antibacterial effect, tissue dissolution efficacy, and the cytotoxicity of the solution were assessed in cell culture and were compared with those of commercial sodium hypochlorite (NaOCl) solutions. Materials and Methods: Trichloroisocyanuric acid (TCA) was used as the source of hypochlorite ions in solution. All required properties of the NaOCl irrigant were evaluated and compared with those of original 2.5% NaOCl solutions currently in use. Results: Our results revealed that a TCA 3.5% + 1/6 Buffer-1 solution passed the short-term stability test. Moreover, no odor of chlorine gas was detected by three independent observers. The hypochlorite ion content and pH were stable over an incubation period of 4 weeks. The new solution did not differ from commercial products in terms of the dissolution property on bovine pulpal tissue (P > 0.05). Moreover, the antibacterial effect of this solution on Enterococcus faecalis did not differ from that of the commercial products (P > 0.05). In addition, our biocompatibility analysis demonstrated no difference among the tested solutions (P > 0.05). Conclusions: According to the results of all properties tested, TCA 3.5% + 1/6 Buffer-1 could be considered an option for NaOCl irrigation with the benefit of no detectable chlorine odor.