Publication: Oxygenated pimarane diterpenes from Kaempferia marginata
Issued Date
2005-11-01
Resource Type
ISSN
01633864
Other identifier(s)
2-s2.0-29044435162
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Natural Products. Vol.68, No.11 (2005), 1632-1636
Suggested Citation
Sanit Thongnest, Chulabhorn Mahidol, Somyote Sutthivaiyakit, Somsak Ruchirawat Oxygenated pimarane diterpenes from Kaempferia marginata. Journal of Natural Products. Vol.68, No.11 (2005), 1632-1636. doi:10.1021/np050186l Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16281
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Title
Oxygenated pimarane diterpenes from Kaempferia marginata
Abstract
Six new diterpenes, (1R,2S,5S,7S,9R,10S,13R)-1,2,7-trihydroxypimara-8(14), 15-diene (1), (1R,2S,5S,9S,10S,11R,13R)-1,2,11-trihydroxypimara-8(14),15-diene (2), (1S,5S,7R,9R,10S,11R,13R)-1,7,11-trihydroxypimara-8(14),15-diene (3), (1S,5S,9S,10S,11R,13R)-1,11-dihydroxypimara-8(14),15-diene (4), (5S,6R,9S,10S,13R)-6-hydroxypimara-8(14),15-diene-1-one (5), and (1R,2S,5S,7S,9R,10S,13R)-1,2-dihydroxypimara-8(14),15-diene-7-one (6), along with four known diterpenes, have been isolated from the dichloromethane extract of whole plants of Kaempferia marginata. The structures were assigned by spectroscopic methods. The absolute configuration of 1 was established by the Mosher ester method. Substances obtained were evaluated against a panel of bioassays including antimalarial, antituberculous, and antifungal activity. © 2005 American Chemical Society and American Society of Pharmacognosy.
