Chulabhorn Mahidol, Hunsa Prawat, Wirongrong Kaweetripob, Somsak Ruchirawat Two new pyranoflavanones from the stems of Derris reticulata. Heterocycles. Vol.57, No.7 (2002), 1287-1292. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/20125
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Two new pyranoflavanones from the stems of Derris reticulata
Two new flavonoids, 4′,5-dihydroxy-8-hydroxymethyl-6″,6″- dimethylpyrano[2′,3′:7,6]flavanone (1), and 2′,3′-dihydroxylupinifolin (2) were isolated from the stems of Derris reticulata. Both compounds showed cytotoxic activity in the P-388 cell line. The structures were established by spectroscopic analysis and chemical transformations. The biosynthetic origin and the mechanism of formation of the hydroxymethyl group in compound (1) are proposed.
