Publication: Molecular stability of chitosan in acid solutions stored at various conditions
Issued Date
2008-02-15
Resource Type
ISSN
10974628
00218995
00218995
Other identifier(s)
2-s2.0-38849180157
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Applied Polymer Science. Vol.107, No.4 (2008), 2588-2593
Suggested Citation
Thi Thanh Binh Nguyen, San Hein, Chuen How Ng, Willem F. Stevens Molecular stability of chitosan in acid solutions stored at various conditions. Journal of Applied Polymer Science. Vol.107, No.4 (2008), 2588-2593. doi:10.1002/app.27376 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/19090
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Title
Molecular stability of chitosan in acid solutions stored at various conditions
Abstract
The stability of chitosan with a degree of deacetylation (DD) of 88 and 81% was investigated in solution during storage for 60 days at various temperatures (60, 28, and 5°C) and acid concentrations (0.8M, 0.2M, and 0.1M). The first-order rate constant of chain hydrolysis of 88%DD chitosan at 60°C was about 1.4 times higher than that of the 81%DD sample. At 28°C, the rates of hydrolysis for both chitosan samples were four to five times lower than those at 60°C and are similar. At 5°C, chain degradation was not significant. Although acetic acid caused significantly higher (P ≤ 0.05) chain scission than formic acid, no significant difference of rate change was observed among three different acid concentrations. Reprecipitation of dissolved chitosan was applied for its purification and to transfer dissolved chitosan to the solvent used to measure its molecular weight. Reprecipitation resulted in slightly lower molecular weight (P ≤ 0.05) for both 88%DD and 81%DD samples. The molecular weight of chitosan before and after reprecipitation had good linear relationship (r2> 0.9). © 2007 Wiley Periodicals, Inc.