Publication: Placebo effect of eutectic mixture of lidocaine and prilocaine (EMLA) cream in reducing venepuncture pain in children
Issued Date
1994-09-07
Resource Type
ISSN
03044602
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2-s2.0-0028075235
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Mahidol University
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SCOPUS
Bibliographic Citation
Annals of the Academy of Medicine Singapore. Vol.23, No.4 (1994), 465-469
Suggested Citation
A. Lurngnateetape, T. Tritrakarn Placebo effect of eutectic mixture of lidocaine and prilocaine (EMLA) cream in reducing venepuncture pain in children. Annals of the Academy of Medicine Singapore. Vol.23, No.4 (1994), 465-469. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/9637
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Title
Placebo effect of eutectic mixture of lidocaine and prilocaine (EMLA) cream in reducing venepuncture pain in children
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Abstract
A randomized double-blind study was made of 60 children aged 5 to 11years to assess the efficacy of a eutectic mixture of local anaesthetics (EMLA), lidocaine and prilocaine, and placebo cream in reducing venepuncture pain. The 5% EMLA or placebo cream, approximately 2 grams (2 ml), was applied to the anticipated venepuncture site and covered with an occlusive dressing for at least 60 minutes. The venepuncture of 20-gauge butterfly needle was done after wiping the skin dry and observing for any local reactions. The pain was evaluated by three methods, one by the investigator and the other two by the children. The results showed that there were no statistical differences in the subject characteristics and pain scores, between the EMLA and the placebo group. Most children in both groups experienced no pain to mild pain from venepuncture. The possible causes were discussed and it was concluded that the placebo effect of having cream and good doctor-children rapport reduced fear and anxiety, resulting in the reduction of venepuncture pain in children.