A 10-year study on the incidence of Oral Maxillofacial lesions in Department of Oral Maxillofacial Surgery, Mahidol University: Keratocystic odontogenic tumor.

Abstract

Introduction: Keratocystic odontogenic tumor (KCOT) is one of the most aggressive odontogenic cysts due to its relatively high recurrence rate, fast growth, and its tendency to invade adjacent tissues. Objective: The aim of the study was to retrospectively analyze the clinico-pathological characteristics of 109 KCOT cases. Materials and methods: <describe the study protocol in short> Results: The study comprised of 46 male and 63 female patients with an age range of 3-87 years with an average age of 32 years. The posterior mandible (48.4%) was the most frequent site of KCOT. Most of the patients were asymptomatic (41%), where as some noted associated swelling, pain, discharge, and paraesthesia. On pathological analysis, 45% of the cystic cavity content was noted to be keratin. On radiologic findings, KCOT appeared as unilocular (83%) as well as multilocular lesions (14%). KCOT was associated with the displacement of impacted teeth; the mandibular third molars (40.37%) were the most frequent impacted teeth. Three patients were confirmed to be associated with nevoid basal cell carcinoma syndrome. Conclusion: Almost all of the lesions were diagnosed histologically as stratified squamous parakeratinized epithelium (90.82%).