Publication: Elevated Japanese encephalitis virus activity monitored by domestic sentinel piglets in Thailand
Issued Date
2011-04-01
Resource Type
ISSN
15303667
Other identifier(s)
2-s2.0-79954523775
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Vector-Borne and Zoonotic Diseases. Vol.11, No.4 (2011), 391-394
Suggested Citation
Narong Nitatpattana, Guillaume Le Flohic, Pattanpon Thongchai, Khajornpong Nakgoi, Somnuek Palaboodeewat, Mimi Khin, Philippe Barbazan, Sutee Yoksan, Jean Paul Gonzalez Elevated Japanese encephalitis virus activity monitored by domestic sentinel piglets in Thailand. Vector-Borne and Zoonotic Diseases. Vol.11, No.4 (2011), 391-394. doi:10.1089/vbz.2010.0035 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/12060
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Elevated Japanese encephalitis virus activity monitored by domestic sentinel piglets in Thailand
Abstract
Twenty-nine domestic piglets from pig farms located in three provinces of Thailand between 2003 and 2004 were used as sentinel animals for Japanese encephalitis virus (JEV) circulation. Piglets were used as sentinel to underline, on one hand, the role of domestic pigs as JEV amplifying host and, on another hand, to point out the interest of using sentinel animals for Japanese encephalitis surveillance. JEV activity was demonstrated through i/ antibody detection using a specific ELISA test for the identification of Immunoglobulins of class M and G, ii/ virus isolation on cell culture, after experimental mosquito inoculation for virus amplification. Almost 100% and 83% of the piglets, respectively, had specific IgG and IgM JEV antibodies and 35% yielded a virus isolate. Piglets of the growing farm industry act as virus amplifier increasing the risk of transmission for the human community. Conclusively, since piglets JEV infection appears early in life and is generally clinically unnoticed, it represents an exceptional sentinel model for human health threats, which has to be considered by health authorities. © 2011, Mary Ann Liebert, Inc.