Publication:
In vivo removal of malaria parasites from red blood cells without their destruction in acute falciparum malaria

Simple item page
dc.contributor.authorBrian J. Angusen_US
dc.contributor.authorKesinee Chotivanichen_US
dc.contributor.authorRachanee Udomsangpetchen_US
dc.contributor.authorNicholas J. Whiteen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-07-04T07:40:12Z
dc.date.available2018-07-04T07:40:12Z
dc.date.issued1997-09-01en_US
dc.description.abstractDuring acute falciparum malaria infection, red blood cells (RBC) containing abundant ring-infected erythrocyte surface antigen (Pf 155 or RESA), but no intracellular parasites, are present in the circulation. These RESA-positive parasite negative RBC are not seen in parasite cultures in vitro. This indicates that in acute falciparum malaria there is active removal of intraerythrocytic parasites by a host mechanism in vivo (probably the spleen) without destruction of the parasitized RBC. This may explain the observed disparity between the drop in hematocrit and decrease in parasite count in some hyperparasitemic patients. The fate of these 'once-parasitized' RBC in vivo is not known.en_US
dc.identifier.citationBlood. Vol.90, No.5 (1997), 2037-2040en_US
dc.identifier.issn00064971en_US
dc.identifier.other2-s2.0-0030921669en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/17884
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0030921669&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleIn vivo removal of malaria parasites from red blood cells without their destruction in acute falciparum malariaen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0030921669&origin=inwarden_US

Files

Collections

Scopus 1991-2000