Publication: Lateral cephalometric analysis and the risks of moderate to severe obstructive sleep-disordered breathing in Thai patients
Issued Date
2013-01-01
Resource Type
ISSN
15221709
15209512
15209512
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2-s2.0-84888638133
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Mahidol University
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SCOPUS
Bibliographic Citation
Sleep and Breathing. Vol.17, No.4 (2013), 1249-1255
Suggested Citation
Wish Banhiran, Pisit Wanichakorntrakul, Choakchai Metheetrairut, Pipat Chiewvit, Wandee Planuphap Lateral cephalometric analysis and the risks of moderate to severe obstructive sleep-disordered breathing in Thai patients. Sleep and Breathing. Vol.17, No.4 (2013), 1249-1255. doi:10.1007/s11325-013-0830-7 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/32593
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Title
Lateral cephalometric analysis and the risks of moderate to severe obstructive sleep-disordered breathing in Thai patients
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Abstract
Purposes: This cross-sectional study was aimed to compare lateral cephalometric parameters among patients with different severities of obstructive sleep-disordered breathing and to determine if there are radiographic variables that increase risk of moderate to severe obstructive sleep apnea (OSA). Methods: Ten linear and 5 angular parameters of lateral cephalometry in 188 adult subjects which included 47 controls and 141 patients with OSA classified by apnea-hypopnea index (AHI) from level-I polysomnography, were analyzed. All radiographs were done under standardized processes and measured twice on separate occasions. Results: There were statistically significant differences between controls and patients with AHI ≥ 15 in parameters such as a distance from mandibular plane to hyoid (MP-H), posterior airway space (PAS), skull base angle (NSBA), a distance from posterior nasal spine to posterior pharyngeal wall (PNS-PP), and soft palate length (PNS-P), (p < 0.01). However, no significant difference was found between controls and mild OSA. Logistic regression analysis showed that only MP-H with cutoff point of ≥ 18 millimeters, NSBA ≤ 130, and PAS ≤ 10 millimeters were independent cephalometric variables that increased risk of having AHI ≥ 15 compared to controls with adjusted odds ratio of 17.1, 8.3 and 4.2, respectively. Gender did not significantly associate with OSA severity in this analysis. Conclusions: Patients who had longer MP-H, narrower PAS and narrower NSBA than specific cutoff points significantly increased risks of moderate to severe OSA. Treatments that effectively improve these parameters, particularly at tongue base level (MP-H and PAS), may decrease the severity of disease. © 2013 Springer-Verlag Berlin Heidelberg.