Publication: Thrombocytopenia in malaria.
Issued Date
1992-03-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0026823820
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
The Southeast Asian journal of tropical medicine and public health. Vol.23, No.1 (1992), 44-50
Suggested Citation
S. Looareesuwan, J. G. Davis, D. L. Allen, S. H. Lee, D. Bunnag, N. J. White Thrombocytopenia in malaria.. The Southeast Asian journal of tropical medicine and public health. Vol.23, No.1 (1992), 44-50. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/22401
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Title
Thrombocytopenia in malaria.
Other Contributor(s)
Abstract
The relationship between platelet counts and platelet bound (direct) or platelet directed (indirect) serum antibody concentrations was studied in 17 patients with Plasmodium falciparum malaria and 12 patients with P. vivax malaria. Platelet counts rose with recovery from infection from 196 +/- 84 x 10(9)/l (mean +/- SD) and 195 +/- 34 x 10(9)/l to 319 +/- 99 and 283 +/- 62 x 10(9)/l respectively (p less than 0.002), but there was no relationship between either absolute platelet count or changes in counts and either indirect or direct platelet antibody levels. These findings suggest that a non-immunologically mediated mechanism is involved in the pathogenesis of thrombocytopenia in malaria.